Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]

Filamentous inclusions made of the microtubule-associated protein tau in a hyperphosphorylated state are a defining feature of a large number of human neurodegenerative diseases. Here we show that (trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (FSB), a fluorescent Congo red...

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Detalles Bibliográficos
Autores principales: Velasco, Ana, Fraser, Graham, Delobel, Patrice, Ghetti, Bernardino, Lavenir, Isabelle, Goedert, Michel
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726283/
https://www.ncbi.nlm.nih.gov/pubmed/18291106
http://dx.doi.org/10.1016/j.febslet.2008.02.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726283/
https://www.ncbi.nlm.nih.gov/pubmed/18291106
http://dx.doi.org/10.1016/j.febslet.2008.02.025

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