In Vivo Analysis of the Notch Receptor S1 Cleavage

A ligand-independent cleavage (S1) in the extracellular domain of the mammalian Notch receptor results in what is considered to be the canonical heterodimeric form of Notch on the cell surface. The in vivo consequences and significance of this cleavage on Drosophila Notch signaling remain unclear an...

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Detalles Bibliográficos
Autores principales: Lake, Robert J., Grimm, Lisa M., Veraksa, Alexey, Banos, Andrew, Artavanis-Tsakonas, Spyros
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726433/
https://www.ncbi.nlm.nih.gov/pubmed/19701455
http://dx.doi.org/10.1371/journal.pone.0006728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726433/
https://www.ncbi.nlm.nih.gov/pubmed/19701455
http://dx.doi.org/10.1371/journal.pone.0006728

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