Cargando…
In Vivo Analysis of the Notch Receptor S1 Cleavage
A ligand-independent cleavage (S1) in the extracellular domain of the mammalian Notch receptor results in what is considered to be the canonical heterodimeric form of Notch on the cell surface. The in vivo consequences and significance of this cleavage on Drosophila Notch signaling remain unclear an...
Autores principales: | Lake, Robert J., Grimm, Lisa M., Veraksa, Alexey, Banos, Andrew, Artavanis-Tsakonas, Spyros |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726433/ https://www.ncbi.nlm.nih.gov/pubmed/19701455 http://dx.doi.org/10.1371/journal.pone.0006728 |
Ejemplares similares
-
The Developmental Role of warthog, the Notch Modifier Encoding Drab6
por: Purcell, Karen, et al.
Publicado: (1999) -
Molecular Structure and Dimeric Organization of the Notch Extracellular Domain as Revealed by Electron Microscopy
por: Kelly, Deborah F., et al.
Publicado: (2010) -
Regulation of ligand-independent Notch signal through intracellular trafficking
por: Hori, Kazuya, et al.
Publicado: (2012) -
The Notch-mediated hyperplasia circuitry in Drosophila reveals a Src-JNK signaling axis
por: Ho, Diana M, et al.
Publicado: (2015) -
Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal
por: Hori, Kazuya, et al.
Publicado: (2011)