Inhibitory Effect of Flavonoids on the Efflux of N-Acetyl 5-Aminosalicylic Acid Intracellularly Formed in Caco-2 Cells

N-acetyl 5-aminosalicylic acid (5-AcASA) that was intracellularly formed from 5-aminosalicylic acid (5-ASA) at 200 μM was discharged 5.3, 7.1, and 8.1-fold higher into the apical site than into the basolateral site during 1, 2, and 4-hour incubations, respectively, in Caco-2 cells grown in Transwell...

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Detalles Bibliográficos
Autores principales: Shin, Yoshimura, Kentaro, Kawano, Ryusuke, Matsumura, Narumi, Sugihara, Koji, Furuno
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726441/
https://www.ncbi.nlm.nih.gov/pubmed/19688110
http://dx.doi.org/10.1155/2009/467489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726441/
https://www.ncbi.nlm.nih.gov/pubmed/19688110
http://dx.doi.org/10.1155/2009/467489

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