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Fission Yeast Tel1(ATM) and Rad3(ATR) Promote Telomere Protection and Telomerase Recruitment

The checkpoint kinases ATM and ATR are redundantly required for maintenance of stable telomeres in diverse organisms, including budding and fission yeasts, Arabidopsis, Drosophila, and mammals. However, the molecular basis for telomere instability in cells lacking ATM and ATR has not yet been elucid...

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Detalles Bibliográficos
Autores principales: Moser, Bettina A., Subramanian, Lakxmi, Khair, Lyne, Chang, Ya-Ting, Nakamura, Toru M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726628/
https://www.ncbi.nlm.nih.gov/pubmed/19714219
http://dx.doi.org/10.1371/journal.pgen.1000622