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Globular Tetramers of β(2)-Microglobulin Assemble into Elaborate Amyloid Fibrils

Amyloid fibrils are ordered polymers in which constituent polypeptides adopt a non-native fold. Despite their importance in degenerative human diseases, the overall structure of amyloid fibrils remains unknown. High-resolution studies of model peptide assemblies have identified residues forming cros...

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Detalles Bibliográficos
Autores principales: White, Helen E., Hodgkinson, Julie L., Jahn, Thomas R., Cohen-Krausz, Sara, Gosal, Walraj S., Müller, Shirley, Orlova, Elena V., Radford, Sheena E., Saibil, Helen R.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726924/
https://www.ncbi.nlm.nih.gov/pubmed/19345691
http://dx.doi.org/10.1016/j.jmb.2009.03.066