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Identification of a Human Cyclin D1-Derived Peptide that Induces Human Cytotoxic CD4 T Cells

Cyclin D1 is over-expressed in various human tumors and therefore can be a potential oncogenic target antigen. However, only a limited number of T cell epitopes has been characterized. We aimed at identifying human cyclin D1-derived peptides that include both CD4 and CD8 T cell epitopes and to test...

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Detalles Bibliográficos
Autores principales: Dao, Tao, Korontsvit, Tatyana, Zakhaleva, Victoria, Haro, Kurtis, Packin, Jonathan, Scheinberg, David A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726944/
https://www.ncbi.nlm.nih.gov/pubmed/19707583
http://dx.doi.org/10.1371/journal.pone.0006730