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Highly Efficient Differentiation and Enrichment of Spinal Motor Neurons Derived from Human and Monkey Embryonic Stem Cells

BACKGROUND: There are no cures or efficacious treatments for severe motor neuron diseases. It is extremely difficult to obtain naïve spinal motor neurons (sMNs) from human tissues for research due to both technical and ethical reasons. Human embryonic stem cells (hESCs) are alternative sources. Seve...

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Detalles Bibliográficos
Autores principales: Wada, Tamaki, Honda, Makoto, Minami, Itsunari, Tooi, Norie, Amagai, Yuji, Nakatsuji, Norio, Aiba, Kazuhiro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726947/
https://www.ncbi.nlm.nih.gov/pubmed/19701462
http://dx.doi.org/10.1371/journal.pone.0006722