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Transmission and spreading of tauopathy in transgenic mouse brain

Hyperphosphorylated tau makes up the filamentous intracellular inclusions of several neurodegenerative diseases, including Alzheimer's disease 1. In the disease process neuronal tau inclusions first appear in transentorhinal cortex, from where they appear to spread to hippocampal formation and...

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Detalles Bibliográficos
Autores principales: Clavaguera, Florence, Bolmont, Tristan, Crowther, R. Anthony, Abramowski, Dorothee, Frank, Stephan, Probst, Alphonse, Fraser, Graham, Stalder, Anna K., Beibel, Martin, Staufenbiel, Matthias, Jucker, Mathias, Goedert, Michel, Tolnay, Markus
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726961/
https://www.ncbi.nlm.nih.gov/pubmed/19503072
http://dx.doi.org/10.1038/ncb1901