Cargando…

The CCR4-NOT Complex Physically and Functionally Interacts with TRAMP and the Nuclear Exosome

BACKGROUND: Ccr4-Not is a highly conserved multi-protein complex consisting in yeast of 9 subunits, including Not5 and the major yeast deadenylase Ccr4. It has been connected functionally in the nucleus to transcription by RNA polymerase II and in the cytoplasm to mRNA degradation. However, there ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Azzouz, Nowel, Panasenko, Olesya O., Colau, Geoffroy, Collart, Martine A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727002/
https://www.ncbi.nlm.nih.gov/pubmed/19707589
http://dx.doi.org/10.1371/journal.pone.0006760