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The CCR4-NOT Complex Physically and Functionally Interacts with TRAMP and the Nuclear Exosome
BACKGROUND: Ccr4-Not is a highly conserved multi-protein complex consisting in yeast of 9 subunits, including Not5 and the major yeast deadenylase Ccr4. It has been connected functionally in the nucleus to transcription by RNA polymerase II and in the cytoplasm to mRNA degradation. However, there ha...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727002/ https://www.ncbi.nlm.nih.gov/pubmed/19707589 http://dx.doi.org/10.1371/journal.pone.0006760 |