Metabolic Control Analysis in a Cellular Model of Elevated MAO-B: Relevance to Parkinson’s Disease

We previously demonstrated that spare respiratory capacity of the TCA cycle enzyme alpha-ketoglutarate dehydrogenase (KGDH) was completely abolished upon increasing levels of MAO-B activity in a dopaminergic cell model system (Kumar et al., J Biol Chem 278:46432–46439, 2003). MAO-B mediated increase...

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Detalles Bibliográficos
Autores principales: Mallajosyula, Jyothi K., Chinta, Shankar J., Rajagopalan, Subramanian, Nicholls, David G., Andersen, Julie K.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727365/
https://www.ncbi.nlm.nih.gov/pubmed/19526285
http://dx.doi.org/10.1007/s12640-009-9032-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727365/
https://www.ncbi.nlm.nih.gov/pubmed/19526285
http://dx.doi.org/10.1007/s12640-009-9032-2

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