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Chaperone-mediated pathway of proteasome regulatory particle assembly

The proteasome regulatory particle (RP) initiates the degradation of ubiquitin-protein conjugates by unfolding the substrate and translocating it into the proteasome core particle (CP) to be degraded1. Here we show that in yeast three proteins are found associated with RP but not RP-CP holoenzyme: N...

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Detalles Bibliográficos
Autores principales: Roelofs, Jeroen, Park, Soyeon, Haas, Wilhelm, Tian, Geng, McAllister, Fiona E., Huo, Ying, Lee, Byung-Hoon, Zhang, Fan, Shi, Yigong, Gygi, Steven P., Finley, Daniel
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727592/
https://www.ncbi.nlm.nih.gov/pubmed/19412159
http://dx.doi.org/10.1038/nature08063