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TGF-β1-induced Migration of Bone Mesenchymal Stem Cells Couples Bone Resorption and Formation

Bone remodeling depends on the precise coordination of bone resorption and subsequent bone formation. Disturbances of this process are associated with skeletal diseases, such as Camurati-Engelmann disease (CED). We show using in vitro and animal models that active TGF-β1 released during bone resorpt...

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Detalles Bibliográficos
Autores principales: Tang, Yi, Wu, Xiangwei, Lei, Weiqi, Pang, Lijuan, Wan, Chao, Shi, Zhenqi, Zhao, Ling, Nagy, Timothy R., Peng, Xinyu, Hu, Junbo, Feng, Xu, Van Hul, Wim, Wan, Mei, Cao, Xu
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727637/
https://www.ncbi.nlm.nih.gov/pubmed/19584867
http://dx.doi.org/10.1038/nm.1979