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In Vivo Expression of MHC Class I Genes Depends on the Presence of a Downstream Barrier Element
Regulation of MHC class I gene expression is critical to achieve proper immune surveillance. In this work, we identify elements downstream of the MHC class I promoter that are necessary for appropriate in vivo regulation: a novel barrier element that protects the MHC class I gene from silencing and...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727697/ https://www.ncbi.nlm.nih.gov/pubmed/19707598 http://dx.doi.org/10.1371/journal.pone.0006748 |