NMDA Receptor Hypofunction Leads to Generalized and Persistent Aberrant γ Oscillations Independent of Hyperlocomotion and the State of Consciousness

BACKGROUND: The psychotomimetics ketamine and MK-801, non-competitive NMDA receptor (NMDAr) antagonists, induce cognitive impairment and aggravate schizophrenia symptoms. In conscious rats, they produce an abnormal behavior associated with a peculiar brain state characterized by increased synchroniz...

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Detalles Bibliográficos
Autores principales: Hakami, Tahir, Jones, Nigel C., Tolmacheva, Elena A., Gaudias, Julien, Chaumont, Joseph, Salzberg, Michael, O'Brien, Terence J., Pinault, Didier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727800/
https://www.ncbi.nlm.nih.gov/pubmed/19707548
http://dx.doi.org/10.1371/journal.pone.0006755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727800/
https://www.ncbi.nlm.nih.gov/pubmed/19707548
http://dx.doi.org/10.1371/journal.pone.0006755

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