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A Novel Role for IκBζ in the Regulation of IFNγ Production

IκBζ is a novel member of the IκB family of NFκB regulators, which modulates NFκB activity in the nucleus, rather than controlling its nuclear translocation. IκBζ is specifically induced by IL-1β and several TLR ligands and positively regulates NFκB-mediated transcription of genes such as IL-6 and N...

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Detalles Bibliográficos
Autores principales: Raices, Raquel M., Kannan, Yashaswini, Bellamkonda-Athmaram, Vedavathi, Seshadri, Sudarshan, Wang, Huating, Guttridge, Denis C., Wewers, Mark D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727951/
https://www.ncbi.nlm.nih.gov/pubmed/19707556
http://dx.doi.org/10.1371/journal.pone.0006776