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New Alzheimer Amyloid β Responsive Genes Identified in Human Neuroblastoma Cells by Hierarchical Clustering

Alzheimer's disease (AD) is characterized by neuronal degeneration and cell loss. Aβ(42), in contrast to Aβ(40), is thought to be the pathogenic form triggering the pathological cascade in AD. In order to unravel overall gene regulation we monitored the transcriptomic responses to increased or...

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Detalles Bibliográficos
Autores principales: Uhrig, Markus, Ittrich, Carina, Wiedmann, Verena, Knyazev, Yuri, Weninger, Annette, Riemenschneider, Matthias, Hartmann, Tobias
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727959/
https://www.ncbi.nlm.nih.gov/pubmed/19707560
http://dx.doi.org/10.1371/journal.pone.0006779