Cargando…

New Alzheimer Amyloid β Responsive Genes Identified in Human Neuroblastoma Cells by Hierarchical Clustering

Alzheimer's disease (AD) is characterized by neuronal degeneration and cell loss. Aβ(42), in contrast to Aβ(40), is thought to be the pathogenic form triggering the pathological cascade in AD. In order to unravel overall gene regulation we monitored the transcriptomic responses to increased or...

Descripción completa

Detalles Bibliográficos
Autores principales:	Uhrig, Markus, Ittrich, Carina, Wiedmann, Verena, Knyazev, Yuri, Weninger, Annette, Riemenschneider, Matthias, Hartmann, Tobias
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727959/ https://www.ncbi.nlm.nih.gov/pubmed/19707560 http://dx.doi.org/10.1371/journal.pone.0006779

Ejemplares similares

Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Aβ(42 )reduces their differentiation potential
por: Uhrig, Markus, et al.
Publicado: (2008)

High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer β-amyloid peptide
por: Rauth, Sabine, et al.
Publicado: (2016)

Spatial Distribution and Hierarchical Clustering of β-Amyloid and Glucose Metabolism in Alzheimer’s Disease
por: Zhou, Da-An, et al.
Publicado: (2022)

Evolutionary Dynamics of Co-Segregating Gene Clusters Associated with Complex Diseases
por: Preuss, Christoph, et al.
Publicado: (2012)

Regulatory feedback cycle of the insulin‐degrading enzyme and the amyloid precursor protein intracellular domain: Implications for Alzheimer’s disease
por: Lauer, Anna A., et al.
Publicado: (2020)

Plasmalogens Inhibit APP Processing by Directly Affecting γ-Secretase Activity in Alzheimer's Disease
por: Rothhaar, Tatjana L., et al.
Publicado: (2012)

Alzheimer’s Disease-Associated Neurotoxic Peptide Amyloid-β Impairs Base Excision Repair in Human Neuroblastoma Cells
por: Forestier, Anne, et al.
Publicado: (2012)

Convex Clustering: An Attractive Alternative to Hierarchical Clustering
por: Chen, Gary K., et al.
Publicado: (2015)

Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease
por: Grimm, Marcus O. W., et al.
Publicado: (2011)

Hierarchical cluster analysis to identify the homogeneous desertification management units
por: Zolfaghari, Farhad, et al.
Publicado: (2019)

Synergistic effects of amyloid peptides and lead on human neuroblastoma cells
por: Suresh, Challa, et al.
Publicado: (2012)

Neuronal Rubicon Represses Extracellular APP/Amyloid β Deposition in Alzheimer’s Disease
por: Espinoza, Sandra, et al.
Publicado: (2022)

Amyloid Precursor Protein (APP) Mediated Regulation of Ganglioside Homeostasis Linking Alzheimer's Disease Pathology with Ganglioside Metabolism
por: Grimm, Marcus O. W., et al.
Publicado: (2012)

Target engagement in an alzheimer trial: Crenezumab lowers amyloid β oligomers in cerebrospinal fluid
por: Yang, Ting, et al.
Publicado: (2019)

K-means and hierarchical clustering with Python
por: Grus, Joel
Publicado: (2016)

Divisive hierarchical maximum likelihood clustering
por: Sharma, Alok, et al.
Publicado: (2017)

Hierarchical clustering of maximum parsimony reconciliations
por: Mawhorter, Ross, et al.
Publicado: (2019)

Unsupervised Hierarchical Clustering Identifies Immune Gene Subtypes in Gastric Cancer
por: Cao, Jing, et al.
Publicado: (2021)

An agglomerative hierarchical clustering approach to visualisation in Bayesian clustering problems
por: Dawson, Kevin J., et al.
Publicado: (2009)

Clinical and biological clusters of sepsis patients using hierarchical clustering
por: Papin, Grégory, et al.
Publicado: (2021)

Plasma Amyloid Concentration in Alzheimer’s Disease: Performance of a High-Throughput Amyloid Assay in Distinguishing Alzheimer’s Disease Cases from Controls
por: Feinkohl, Insa, et al.
Publicado: (2020)

Tocotrienol Affects Oxidative Stress, Cholesterol Homeostasis and the Amyloidogenic Pathway in Neuroblastoma Cells: Consequences for Alzheimer’s Disease
por: Grimm, Marcus O. W., et al.
Publicado: (2016)

Structural Brain Imaging Phenotypes of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) Found by Hierarchical Clustering
por: Kärkkäinen, Mikko, et al.
Publicado: (2020)

Plasma Exosomes Spread and Cluster Around β-Amyloid Plaques in an Animal Model of Alzheimer’s Disease
por: Zheng, Tingting, et al.
Publicado: (2017)

Impact of Amyloid-β on Platelet Mitochondrial Function and Platelet–Mediated Amyloid Aggregation in Alzheimer’s Disease
por: Donner, Lili, et al.
Publicado: (2021)

Development of Beta-Amyloid-Specific CAR-Tregs for the Treatment of Alzheimer’s Disease
por: Saetzler, Valerie, et al.
Publicado: (2023)

Large scale hierarchical clustering of protein sequences
por: Krause, Antje, et al.
Publicado: (2005)

Resolving the structure of interactomes with hierarchical agglomerative clustering
por: Park, Yongjin, et al.
Publicado: (2011)

Detection of Significant Groups in Hierarchical Clustering by Resampling
por: Sebastiani, Paola, et al.
Publicado: (2016)

Hierarchical clusters in families with type 2 diabetes
por: García-Solano, Beatriz, et al.
Publicado: (2015)

Using Permutations for Hierarchical Clustering of Time Series
por: Cánovas, Jose S., et al.
Publicado: (2019)

Fast tree aggregation for consensus hierarchical clustering
por: Hulot, Audrey, et al.
Publicado: (2020)

Renyi entropy driven hierarchical graph clustering
por: Oggier, Frédérique, et al.
Publicado: (2021)

A hierarchical clustering approach to identify repeated enrollments in web survey data
por: Handorf, Elizabeth A., et al.
Publicado: (2018)

Identifying responders to elamipretide in Barth syndrome: Hierarchical clustering for time series data
por: Van den Eynde, Jef, et al.
Publicado: (2023)

Direct Observation of α-Synuclein Amyloid Aggregates in Endocytic Vesicles of Neuroblastoma Cells
por: Apetri, Mihaela M., et al.
Publicado: (2016)

PathCluster: a framework for gene set-based hierarchical clustering
por: Kim, Tae-Min, et al.
Publicado: (2008)

Selection of informative clusters from hierarchical cluster tree with gene classes
por: Toronen, Petri
Publicado: (2004)

The structure of nearby clusters of galaxies Hierarchical clustering and an application to the Leo region
por: Materne, J
Publicado: (1978)

Clustering Acoustic Segments Using Multi-Stage Agglomerative Hierarchical Clustering
por: Lerato, Lerato, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_lnpgvk90ob9ovl0dp13f4osog0