Intervention in gene regulatory networks via greedy control policies based on long-run behavior

BACKGROUND: A salient purpose for studying gene regulatory networks is to derive intervention strategies, the goals being to identify potential drug targets and design gene-based therapeutic intervention. Optimal stochastic control based on the transition probability matrix of the underlying Markov...

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Detalles Bibliográficos
Autores principales: Qian, Xiaoning, Ivanov, Ivan, Ghaffari, Noushin, Dougherty, Edward R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728102/
https://www.ncbi.nlm.nih.gov/pubmed/19527511
http://dx.doi.org/10.1186/1752-0509-3-61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728102/
https://www.ncbi.nlm.nih.gov/pubmed/19527511
http://dx.doi.org/10.1186/1752-0509-3-61

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