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Intervention in gene regulatory networks via greedy control policies based on long-run behavior
BACKGROUND: A salient purpose for studying gene regulatory networks is to derive intervention strategies, the goals being to identify potential drug targets and design gene-based therapeutic intervention. Optimal stochastic control based on the transition probability matrix of the underlying Markov...
Autores principales: | Qian, Xiaoning, Ivanov, Ivan, Ghaffari, Noushin, Dougherty, Edward R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728102/ https://www.ncbi.nlm.nih.gov/pubmed/19527511 http://dx.doi.org/10.1186/1752-0509-3-61 |
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