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Ribosomal Synthesis of N-Methyl Peptides
[Image: see text] N-Methyl amino acids (N-Me AAs) are a common component of nonribosomal peptides (NRPs), a class of natural products from which many clinically important therapeutics are obtained. N-Me AAs confer peptides with increased conformational rigidity, membrane permeability, and protease r...
Autores principales: | Subtelny, Alexander O., Hartman, Matthew C. T., Szostak, Jack W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728122/ https://www.ncbi.nlm.nih.gov/pubmed/18402453 http://dx.doi.org/10.1021/ja710016v |
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