NEMO/IKKγ regulates an early NF-κB-independent cell death checkpoint during TNF signaling

TNF receptor 1 (TNFR1) ligation can result in cell survival or cell death. What determines which of the two opposing responses is triggered is not fully understood. The current model suggests that it is the activation of the NF-κB pathway and its induction of pro-survival genes, or the lack thereof,...

Descripción completa

Detalles Bibliográficos
Autores principales: Legarda-Addison, Diana, Hase, Hidenori, O'Donnell, Marie Anne, Ting, Adrian T.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728158/
https://www.ncbi.nlm.nih.gov/pubmed/19373245
http://dx.doi.org/10.1038/cdd.2009.41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728158/
https://www.ncbi.nlm.nih.gov/pubmed/19373245
http://dx.doi.org/10.1038/cdd.2009.41

Ejemplares similares