Probing the urea dependence of residual structure in denatured human α-lactalbumin

Backbone (15)N relaxation parameters and (15)N–(1)H(N) residual dipolar couplings (RDCs) have been measured for a variant of human α-lactalbumin (α-LA) in 4, 6, 8 and 10 M urea. In the α-LA variant, the eight cysteine residues in the protein have been replaced by alanines (all-Ala α-LA). This protei...

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Detalles Bibliográficos
Autores principales: Higman, Victoria A., Rösner, Heike I., Ugolini, Raffaella, Greene, Lesley H., Redfield, Christina, Smith, Lorna J.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728226/
https://www.ncbi.nlm.nih.gov/pubmed/19618277
http://dx.doi.org/10.1007/s10858-009-9342-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728226/
https://www.ncbi.nlm.nih.gov/pubmed/19618277
http://dx.doi.org/10.1007/s10858-009-9342-y

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