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Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors

Heart disease is the leading cause of mortality and morbidity in the Western world. The heart has little regenerative capacity after damage, leading to much interest in understanding the factors required to produce new cardiac myocytes. Despite a robust understanding of the molecular networks regula...

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Detalles Bibliográficos
Autores principales: Takeuchi, Jun K., Bruneau, Benoit G.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728356/
https://www.ncbi.nlm.nih.gov/pubmed/19396158
http://dx.doi.org/10.1038/nature08039