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The impact of copy number variation on local gene expression in mouse hematopoietic stem/progenitor cells

The extent to which differences in germ line DNA copy number contribute to natural phenotypic variation is unknown. We analyzed the copy number content of the mouse genome to a sub-10 kb resolution. We identified over 1,300 copy number variant regions (CNVRs), most of which are < 10 kb in length,...

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Detalles Bibliográficos
Autores principales: Cahan, Patrick, Li, Yedda, Izumi, Masayo, Graubert, Timothy A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728431/
https://www.ncbi.nlm.nih.gov/pubmed/19270704
http://dx.doi.org/10.1038/ng.350