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Characterisation of the passive permeability barrier of nuclear pore complexes

Nuclear pore complexes (NPCs) restrict uncontrolled nucleocytoplasmic fluxes of inert macromolecules but permit facilitated translocation of nuclear transport receptors and their cargo complexes. We probed the passive barrier of NPCs and observed sieve-like properties with a dominating mesh or chann...

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Detalles Bibliográficos
Autores principales: Mohr, Dagmar, Frey, Steffen, Fischer, Torsten, Güttler, Thomas, Görlich, Dirk
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728435/
https://www.ncbi.nlm.nih.gov/pubmed/19680228
http://dx.doi.org/10.1038/emboj.2009.200