microRNA-Mediated Messenger RNA Deadenylation Contributes to Translational Repression in Mammalian Cells

Animal microRNAs (miRNAs) typically regulate gene expression by binding to partially complementary target sites in the 3′ untranslated region (UTR) of messenger RNA (mRNA) reducing its translation and stability. They also commonly induce shortening of the mRNA 3′ poly(A) tail, which contributes to t...

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Detalles Bibliográficos
Autores principales: Beilharz, Traude H., Humphreys, David T., Clancy, Jennifer L., Thermann, Rolf, Martin, David I. K., Hentze, Matthias W., Preiss, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728509/
https://www.ncbi.nlm.nih.gov/pubmed/19710908
http://dx.doi.org/10.1371/journal.pone.0006783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728509/
https://www.ncbi.nlm.nih.gov/pubmed/19710908
http://dx.doi.org/10.1371/journal.pone.0006783

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