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Dosage compensation on the active X chromosome minimizes transcriptional noise of X-linked genes in mammals
BACKGROUND: Theory predicts that haploid-expressed genes should have noisier expression than comparable diploid-expressed ones with the same expression level. However, in mammals there are several classes of gene that are monoallelically expressed, including X-linked genes, imprinted genes and some...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728528/ https://www.ncbi.nlm.nih.gov/pubmed/19594925 http://dx.doi.org/10.1186/gb-2009-10-7-r74 |