Dosage compensation on the active X chromosome minimizes transcriptional noise of X-linked genes in mammals

BACKGROUND: Theory predicts that haploid-expressed genes should have noisier expression than comparable diploid-expressed ones with the same expression level. However, in mammals there are several classes of gene that are monoallelically expressed, including X-linked genes, imprinted genes and some...

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Detalles Bibliográficos
Autores principales: Yin, Shanye, Wang, Ping, Deng, Wenjun, Zheng, Hancheng, Hu, Landian, Hurst, Laurence D, Kong, Xiangyin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728528/
https://www.ncbi.nlm.nih.gov/pubmed/19594925
http://dx.doi.org/10.1186/gb-2009-10-7-r74

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