Inhibition of StearoylCoA Desaturase-1 Inactivates Acetyl-CoA Carboxylase and Impairs Proliferation in Cancer Cells: Role of AMPK

Cancer cells activate the biosynthesis of saturated fatty acids (SFA) and monounsaturated fatty acids (MUFA) in order to sustain an increasing demand for phospholipids with appropriate acyl composition during cell replication. We have previously shown that a stable knockdown of stearoyl-CoA desatura...

Descripción completa

Detalles Bibliográficos
Autores principales: Scaglia, Natalia, Chisholm, Jeffrey W., Igal, R. Ariel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728543/
https://www.ncbi.nlm.nih.gov/pubmed/19710915
http://dx.doi.org/10.1371/journal.pone.0006812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728543/
https://www.ncbi.nlm.nih.gov/pubmed/19710915
http://dx.doi.org/10.1371/journal.pone.0006812

Ejemplares similares