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A Cellular Model To Monitor Proteasome Dysfunction by α-Synuclein†

[Image: see text] Impairment of the ubiquitin-proteasome degradation system has recently been suggested to be related to the onset of neurodegenerative disorders such as Alzheimer′s disease and Parkinson's disease. In this study, we investigated whether intracellular α-synuclein affects proteas...

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Detalles Bibliográficos
Autores principales: Nonaka, Takashi, Hasegawa, Masato
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728579/
https://www.ncbi.nlm.nih.gov/pubmed/19630439
http://dx.doi.org/10.1021/bi900619j