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Directed neuronal differentiation of human embryonic stem cells

BACKGROUND: We have developed a culture system for the efficient and directed differentiation of human embryonic stem cells (HESCs) to neural precursors and neurons. HESC were maintained by manual passaging and were differentiated to a morphologically distinct OCT-4(+)/SSEA-4(- )monolayer cell type...

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Detalles Bibliográficos
Autores principales: Schulz, Thomas C, Palmarini, Gail M, Noggle, Scott A, Weiler, Deborah A, Mitalipova, Maisam M, Condie, Brian G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC272931/
https://www.ncbi.nlm.nih.gov/pubmed/14572319
http://dx.doi.org/10.1186/1471-2202-4-27