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ABT-869, a promising multi-targeted tyrosine kinase inhibitor: from bench to bedside
Tyrosine Kinase Inhibitors (TKI) have significantly changed the landscape of current cancer therapy. Understanding of mechanisms of aberrant TK signaling and strategies to inhibit TKs in cancer, further promote the development of novel agents. ABT-869, a novel ATP-competitive receptor tyrosine kinas...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729745/ https://www.ncbi.nlm.nih.gov/pubmed/19642998 http://dx.doi.org/10.1186/1756-8722-2-33 |