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No Seasonal Accumulation of Resistant P. falciparum when High-Dose Chloroquine Is Used

BACKGROUND: Potentially chloroquine resistant P. falciparum, identified by the 76T haplotype in the chloroquine resistance transporter (pfcrt 76T), are highly prevalent throughout Africa. In Guinea-Bissau, normal and double dose chloroquine have respective efficacies of 34% and 78% against P.falcipa...

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Detalles Bibliográficos
Autores principales: Ursing, Johan, Kofoed, Poul-Erik, Rodrigues, Amabelia, Rombo, Lars
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729929/
https://www.ncbi.nlm.nih.gov/pubmed/19718439
http://dx.doi.org/10.1371/journal.pone.0006866