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No Seasonal Accumulation of Resistant P. falciparum when High-Dose Chloroquine Is Used
BACKGROUND: Potentially chloroquine resistant P. falciparum, identified by the 76T haplotype in the chloroquine resistance transporter (pfcrt 76T), are highly prevalent throughout Africa. In Guinea-Bissau, normal and double dose chloroquine have respective efficacies of 34% and 78% against P.falcipa...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729929/ https://www.ncbi.nlm.nih.gov/pubmed/19718439 http://dx.doi.org/10.1371/journal.pone.0006866 |