The Inhibitory Effect of siRNAs on The High Glucose-Induced Overexpression of TGF-β1 in Mesangial Cells

Diabetic nephropathy is characterized by an expansion of the glomerular mesangium, caused by mesangial cell proliferation and an excessive accumulation of extracellar matrix (ECM) proteins, which eventually leading to glomerulosclerosis. TGF-β1 was found to play an important role in the accumulation...

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Detalles Bibliográficos
Autores principales: Noh, Hey-Jeong, Kim, Hyun-Chul, Lee, Sang-Sook, Kang, Yu-Na, Chae, Young-Mi, Park, Kwan-Kyu
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2006
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729946/
https://www.ncbi.nlm.nih.gov/pubmed/16778384
http://dx.doi.org/10.3346/jkms.2006.21.3.430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729946/
https://www.ncbi.nlm.nih.gov/pubmed/16778384
http://dx.doi.org/10.3346/jkms.2006.21.3.430

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