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Powerful Bivariate Genome-Wide Association Analyses Suggest the SOX6 Gene Influencing Both Obesity and Osteoporosis Phenotypes in Males

BACKGROUND: Current genome-wide association studies (GWAS) are normally implemented in a univariate framework and analyze different phenotypes in isolation. This univariate approach ignores the potential genetic correlation between important disease traits. Hence this approach is difficult to detect...

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Detalles Bibliográficos
Autores principales: Liu, Yao-Zhong, Pei, Yu-Fang, Liu, Jian-Feng, Yang, Fang, Guo, Yan, Zhang, Lei, Liu, Xiao-Gang, Yan, Han, Wang, Liang, Zhang, Yin-Ping, Levy, Shawn, Recker, Robert R., Deng, Hong-Wen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730014/
https://www.ncbi.nlm.nih.gov/pubmed/19714249
http://dx.doi.org/10.1371/journal.pone.0006827