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Human Condensin Function Is Essential for Centromeric Chromatin Assembly and Proper Sister Kinetochore Orientation

Condensins I and II in vertebrates are essential ATP-dependent complexes necessary for chromosome condensation in mitosis. Condensins depletion is known to perturb structure and function of centromeres, however the mechanism of this functional link remains elusive. Depletion of condensin activity is...

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Detalles Bibliográficos
Autores principales: Samoshkin, Alexander, Arnaoutov, Alexei, Jansen, Lars E. T., Ouspenski, Ilia, Dye, Louis, Karpova, Tatiana, McNally, James, Dasso, Mary, Cleveland, Don W., Strunnikov, Alexander
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730017/
https://www.ncbi.nlm.nih.gov/pubmed/19714251
http://dx.doi.org/10.1371/journal.pone.0006831