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Shiga Toxin Receptor Gb3Cer/CD77: Tumor-Association and Promising Therapeutic Target in Pancreas and Colon Cancer

BACKGROUND: Despite progress in adjuvant chemotherapy in the recent decades, pancreatic and colon cancers remain common causes of death worldwide. Bacterial toxins, which specifically bind to cell surface-exposed glycosphingolipids, are a potential novel therapy. We determined the expression of glob...

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Detalles Bibliográficos
Autores principales: Distler, Ute, Souady, Jamal, Hülsewig, Marcel, Drmić-Hofman, Irena, Haier, Jörg, Friedrich, Alexander W., Karch, Helge, Senninger, Norbert, Dreisewerd, Klaus, Berkenkamp, Stefan, Schmidt, M. Alexander, Peter-Katalinić, Jasna, Müthing, Johannes
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730034/
https://www.ncbi.nlm.nih.gov/pubmed/19714252
http://dx.doi.org/10.1371/journal.pone.0006813