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Xpf and Not the Fanconi Anaemia Proteins or Rev3 Accounts for the Extreme Resistance to Cisplatin in Dictyostelium discoideum

Organisms like Dictyostelium discoideum, often referred to as DNA damage “extremophiles”, can survive exposure to extremely high doses of radiation and DNA crosslinking agents. These agents form highly toxic DNA crosslinks that cause extensive DNA damage. However, little is known about how Dictyoste...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Yin, Langenick, Judith, Traynor, David, Babu, M. Madan, Kay, Rob R., Patel, Ketan J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730050/
https://www.ncbi.nlm.nih.gov/pubmed/19763158
http://dx.doi.org/10.1371/journal.pgen.1000645