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A molecular analysis of biclonal follicular lymphoma: further evidence for bone marrow origin and clonal selection

We report a follicular lymphoma (FL) case presenting the coexistence of two tumor cell subpopulations in lymph node (LN) and bone marrow (BM), which exhibited an inverse pattern of immunoglobulin light (IgL) chain gene rearrangement and expression: Igκ−λ+ in LN and Igκ+λ− in BM. These tumor clones s...

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Detalles Bibliográficos
Autores principales: Nakamura, Yuichi, Sato, Yasutaka, Yoshida, Katsuhiko, Kakegawa, Emi, Ito, Yoshihiro, Seyama, Atsushi, Kayano, Hidekazu, Bessho, Masami
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730550/
https://www.ncbi.nlm.nih.gov/pubmed/19220419
http://dx.doi.org/10.1111/j.1600-0609.2009.01233.x