Lysosomal localization of GLUT8 in the testis – the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction

The class III sugar transport facilitator GLUT8 co-localizes with the lysosomal protein LAMP1 in heterologous expression systems. GLUT8 carries a [D/E]XXXL[L/I]-type dileucine sorting signal that has been postulated to retain the protein in an endosomal/lysosomal compartment via interactions with cl...

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Detalles Bibliográficos
Autores principales: Diril, Muhammed Kasim, Schmidt, Stefan, Krauß, Michael, Gawlik, Verena, Joost, Hans-Georg, Schürmann, Annette, Haucke, Volker, Augustin, Robert
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730553/
https://www.ncbi.nlm.nih.gov/pubmed/19523115
http://dx.doi.org/10.1111/j.1742-4658.2009.07089.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730553/
https://www.ncbi.nlm.nih.gov/pubmed/19523115
http://dx.doi.org/10.1111/j.1742-4658.2009.07089.x

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