A Systems Genetics Approach Implicates USF1, FADS3, and Other Causal Candidate Genes for Familial Combined Hyperlipidemia

We hypothesized that a common SNP in the 3' untranslated region of the upstream transcription factor 1 (USF1), rs3737787, may affect lipid traits by influencing gene expression levels, and we investigated this possibility utilizing the Mexican population, which has a high predisposition to dysl...

Descripción completa

Detalles Bibliográficos
Autores principales: Plaisier, Christopher L., Horvath, Steve, Huertas-Vazquez, Adriana, Cruz-Bautista, Ivette, Herrera, Miguel F., Tusie-Luna, Teresa, Aguilar-Salinas, Carlos, Pajukanta, Päivi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730565/
https://www.ncbi.nlm.nih.gov/pubmed/19750004
http://dx.doi.org/10.1371/journal.pgen.1000642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730565/
https://www.ncbi.nlm.nih.gov/pubmed/19750004
http://dx.doi.org/10.1371/journal.pgen.1000642

Ejemplares similares