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A Systems Genetics Approach Implicates USF1, FADS3, and Other Causal Candidate Genes for Familial Combined Hyperlipidemia
We hypothesized that a common SNP in the 3' untranslated region of the upstream transcription factor 1 (USF1), rs3737787, may affect lipid traits by influencing gene expression levels, and we investigated this possibility utilizing the Mexican population, which has a high predisposition to dysl...
Autores principales: | Plaisier, Christopher L., Horvath, Steve, Huertas-Vazquez, Adriana, Cruz-Bautista, Ivette, Herrera, Miguel F., Tusie-Luna, Teresa, Aguilar-Salinas, Carlos, Pajukanta, Päivi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730565/ https://www.ncbi.nlm.nih.gov/pubmed/19750004 http://dx.doi.org/10.1371/journal.pgen.1000642 |
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