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Fast Mapping of Short Sequences with Mismatches, Insertions and Deletions Using Index Structures

With few exceptions, current methods for short read mapping make use of simple seed heuristics to speed up the search. Most of the underlying matching models neglect the necessity to allow not only mismatches, but also insertions and deletions. Current evaluations indicate, however, that very differ...

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Detalles Bibliográficos
Autores principales: Hoffmann, Steve, Otto, Christian, Kurtz, Stefan, Sharma, Cynthia M., Khaitovich, Philipp, Vogel, Jörg, Stadler, Peter F., Hackermüller, Jörg
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730575/
https://www.ncbi.nlm.nih.gov/pubmed/19750212
http://dx.doi.org/10.1371/journal.pcbi.1000502