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Fast Mapping of Short Sequences with Mismatches, Insertions and Deletions Using Index Structures
With few exceptions, current methods for short read mapping make use of simple seed heuristics to speed up the search. Most of the underlying matching models neglect the necessity to allow not only mismatches, but also insertions and deletions. Current evaluations indicate, however, that very differ...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730575/ https://www.ncbi.nlm.nih.gov/pubmed/19750212 http://dx.doi.org/10.1371/journal.pcbi.1000502 |