The CREB Coactivator CRTC2 Links Hepatic ER Stress and Fasting Gluconeogenesis

In fasted mammals, circulating pancreatic glucagon stimulates hepatic gluconeogenesis in part through the CREB Regulated Transcription Coactivator 2 (CRTC2; also referred to as TORC2) 1,2. Hepatic glucose production is elevated in obesity, reflecting chronic increases in endoplasmic reticulum (ER) s...

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Detalles Bibliográficos
Autores principales: Wang, Yiguo, Vera, Liliana, Fischer, Wolfgang H., Montminy, Marc
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730924/
https://www.ncbi.nlm.nih.gov/pubmed/19543265
http://dx.doi.org/10.1038/nature08111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730924/
https://www.ncbi.nlm.nih.gov/pubmed/19543265
http://dx.doi.org/10.1038/nature08111

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