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RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension

Pulmonary arterial hypertension (PAH) is a devastating disease characterized by progressive elevation of pulmonary arterial pressure and vascular resistance due to pulmonary vasoconstriction and vessel remodeling as well as inflammation. Rho-kinases (ROCKs) are one of the best-described effectors of...

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Detalles Bibliográficos
Autores principales: Barman, Scott A, Zhu, Shu, White, Richard E
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731064/
https://www.ncbi.nlm.nih.gov/pubmed/19707285