Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice

BACKGROUND: Lats1 (large tumor suppressor 1) codes for a serine/threonine kinase that plays a role in the progression through mitosis. Genetic studies demonstrated that the loss of LATS1 in mouse, and of its ortholog wts (warts) in Drosophila, is associated with increased cancer incidence. There are...

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Detalles Bibliográficos
Autores principales: Siam, Rania, Harada, Ryoko, Cadieux, Chantal, Battat, Robert, Vadnais, Charles, Nepveu, Alain
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731069/
https://www.ncbi.nlm.nih.gov/pubmed/19656388
http://dx.doi.org/10.1186/1476-4598-8-60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731069/
https://www.ncbi.nlm.nih.gov/pubmed/19656388
http://dx.doi.org/10.1186/1476-4598-8-60

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