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Beyond blood brain barrier breakdown – in vivo detection of occult neuroinflammatory foci by magnetic nanoparticles in high field MRI

BACKGROUND: Gadopentate dimeglumine (Gd-DTPA) enhanced magnetic resonance imaging (MRI) is widely applied for the visualization of blood brain barrier (BBB) breakdown in multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). Recently, the potential of magnetic nano...

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Detalles Bibliográficos
Autores principales: Tysiak, Eva, Asbach, Patrick, Aktas, Orhan, Waiczies, Helmar, Smyth, Maureen, Schnorr, Joerg, Taupitz, Matthias, Wuerfel, Jens
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731086/
https://www.ncbi.nlm.nih.gov/pubmed/19660125
http://dx.doi.org/10.1186/1742-2094-6-20