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Raltegravir Cerebrospinal Fluid Concentrations in HIV-1 Infection

INTRODUCTION: Raltegravir is an HIV-1 integrase inhibitor currently used in treatment-experienced HIV-1-infected patients resistant to other drug classes. In order to assess its central nervous system penetration, we measured raltegravir concentrations in cerebrospinal fluid (CSF) and plasma in subj...

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Detalles Bibliográficos
Autores principales: Yilmaz, Aylin, Gisslén, Magnus, Spudich, Serena, Lee, Evelyn, Jayewardene, Anura, Aweeka, Francesca, Price, Richard W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731205/
https://www.ncbi.nlm.nih.gov/pubmed/19721718
http://dx.doi.org/10.1371/journal.pone.0006877